Nutritional Value of a Slice of Pizza by Type and Crust

A plain cheese slice from a medium pie lands around 261 calories, but the nutritional value of a slice of pizza swings hard once you factor in crust thickness, cheese load, and toppings. Two slices from the same box can differ by 200 calories, which is why guessing pizza calories rarely works.

The numbers below break down the nutritional value of a slice of pizza by crust and topping, with real per slice figures for cheese, pepperoni, thin crust, and deep dish. Every count here comes from published nutrition data, so you can log dinner without turning it into a math project.

Nutritional Value of a Slice of Pizza at a Glance

One slice of standard cheese pizza, about 109 grams, carries roughly 261 calories, 12 grams of protein, 29 grams of carbs, 11 grams of fat, and 661 milligrams of sodium, based on USDA style nutrition data. That sodium figure is close to a third of the daily limit many adults aim for, and it climbs fast once cured meats join the pie.

A single slice can range from about 135 calories for a personal pan cut to 535 calories for Chicago deep dish, a fourfold spread from what looks like the same food.

Pizza Slice Calories by Crust, Thin to Deep Dish

Crust is the biggest lever on pizza calories. As a rough map, thin crust runs 150 to 250 calories per slice, regular hand tossed sits at 250 to 350, deep dish reaches 350 to 500, and stuffed crust often clears 500 because of the cheese sealed inside the edge.

Thin Crust Pizza Calories

Thin crust is the easiest win for anyone watching intake. A slice of Domino's thin crust pepperoni is about 215 calories, and most thin crust pepperoni slices fall between 230 and 280. Swapping one regular slice for thin crust saves roughly 75 to 115 calories.

Deep Dish and Stuffed Crust

Deep dish is a different food. A slice of Chicago deep dish packs about 535 calories, 26 grams of fat, and 44 grams of carbs, while a Detroit style square runs near 320 calories, based on a per slice style breakdown. Stuffed crust pushes even higher once the extra mozzarella is counted.

Cheese Pizza Calories vs Pepperoni Pizza Calories

A plain cheese slice sets the baseline at roughly 250 to 285 calories. Pepperoni is the most common upgrade, and it adds about 50 to 80 calories to that same slice, mostly from fat. Sausage adds 50 to 90, while a few grilled chicken strips add only about 25.

Put together, pepperoni slices usually land between 300 and 400 calories depending on crust and size. If you love pepperoni, thin crust is the trick that keeps a two slice serving near 500 calories instead of 700.

Pepperoni adds only about 50 to 80 calories per slice over plain cheese, so your crust choice usually matters more than the meat on top.

Pizza Hut Calories, Dominos Calories and the Chains

Chain slices vary by size and crust, so the label matters. Pizza Hut calories for a medium hand tossed pepperoni slice are about 230, rising to 310 for a large slice, based on published chain nutrition data. Domino's calories for a medium hand tossed pepperoni slice sit near 200, and a large runs about 300.

Little Caesars pizza calories for a 14 inch round pepperoni slice come in around 280. Across every chain the pattern holds, larger slices and thicker crust mean more calories, so checking the official slice count before you order pays off.

How Many Slices in a Large Pizza and Total Calories

A large 14 inch pizza is usually cut into 8 slices, so the whole pie adds up fast. At 300 calories per pepperoni slice, a large runs about 2,400 calories total, which is more than a full day for many people. Knowing how many slices in a large pizza there are makes portioning simple.

A large 14 inch pie cut into 8 slices can top 2,400 calories, so the box, not the slice, is often the real portion trap on pizza night.

How to Track Pizza Without the Guesswork

The fastest way to log pizza is to snap a photo and let AI estimate the calories and macros. CalMeal reads your plate, flags the crust and toppings, and returns a per slice estimate in seconds, so pizza night fits your day instead of derailing it. For the full pizza slice nutrition picture, pair that estimate with the counts above.

Pizza rarely shows up alone, so it helps to know the rest of your plate. Compare it with our avocado macros guide, check a lean protein in the rotisserie chicken breakdown, and set your daily target with the maintenance calorie calculator. You can also browse more food counts on our blog.

Common Questions About Pizza Nutrition

How Many Calories in a Slice of Pizza?

Most slices land between 200 and 400 calories. A plain cheese slice is about 250 to 285, a pepperoni slice runs 300 to 400, and a thin crust slice can dip to 150 to 250. Crust and slice size drive the answer more than any single topping.

How Many Calories in a Piece of Pizza?

A piece and a slice mean the same thing here, so the same range applies, roughly 200 to 400 calories. To pin the exact number, note the crust and whether the pie was medium or large, then match it to the chain's published slice count.

How Many Slices in a Large Pizza?

A large 14 inch pizza is typically cut into 8 slices, a medium 12 inch gives about 8 smaller slices, and an extra large 16 to 18 inch can be cut into 10 or 12. Fewer, bigger slices mean more calories each, so the cut count changes your per slice math.

Pizza fits a healthy week when you can see the numbers behind each slice. Take the guesswork out of pizza night and every other meal with AI powered food recognition that estimates calories and macros from a single photo. Get the app here: iOS or Android.